A2M Monoclonal Antibody

Supplier: Elabscience
Product Type: monoclonal antibody
Clone No: Clone:117
Description: alpha-2-macroglobulin,also known as ?2-macroglobulin (?2M and A2M),is a protein abundant in the plasma of vertebrates and several invertebrates. A2M is an evolutionarily conserved arm of the innate immune system. It also mediates the proliferation of T cells and macrophages. A2M acts as a nonspecific protease inhibitor involved in the host defense mechanism that inactivates both endogenous and exogenous proteases,including trypsin,thrombin and collagenase. Even though A2M is produced predominantly by the liver,it may also be expressed in the reproductive tract,heart,and brain,and may have important roles in many physiological processes and medical illnesses including Alzheimer’s disease.
Research Areas: Cancer, Cell Biology, Cardiovascular
Size: 200 uL
Concentration: 1mg/mL
Swissprot: P01023
Gene ID: 2
Gene Accession:
Applications: WB,IHC,IF,ELISA
Recommended Dilutions: WB 1:500-1:5000, IHC 1:20-1:200, IF 1:50-1:500
Reactivity: Human
Host: Mouse
Isotype: IgG2a
Immunogen: Fusion protein of Alpha-2-macroglobulin
Formulation: PBS with 0.02% sodium azide, 50% glycerol, PH7.3
Purification: Protein A purification
Conjugation: Unconjugated
Calculated MW: 1474aa, 163kDa
Obeserved MW: 185kDa
Storage: Store at -20C. Avoid freeze / thaw cycles.
Tissue Specificity/Positive Control: Secreted in plasma.
Cellular Localization: Secreted.

Product Link: https://www.elabscience.com/p-a2m_monoclonal_antibody-24768.html
Manual Link: https://www.elabscience.com/viewpdf-24768-elabscience-E-AB-27021.PDF