ABCA8 Polyclonal Antibody

Supplier: Elabscience
Product Type: Antibody
Clonality: Polyclonal
Descritpion: The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. The encoded protein may regulate lipid metabolism and be involved in the formation and maintenance of myelin. Alternative splicing results in multiple transcript variants.ABCA8 (ATP Binding Cassette Subfamily A Member 8) is a Protein Coding gene. Among its related pathways are Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds and CDK-mediated phosphorylation and removal of Cdc6. GO annotations related to this gene include GTP binding and ATPase activity. An important paralog of this gene is ABCA9.
Research Areas: Cancer, Metabolism, Signal transduction
Applications: WB,ELISA
Recommended Dilutions: WB 1:500-1:2000, ELISA 1:40000
Size: 200 uL
Concentration: 1mg/mL
Swissprot: O94911
Gene Accession:
Reactivity: Human,Mouse
Host: Rabbit
Isotype: IgG
Immunogen: Synthesized peptide derived from the Internal region of human ABCA8
Formulation: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Purification: Affinity purification
Conjugation: Unconjugated
Calculated MW: 179kDa
Tissue Specificity/Positive Control: Widely expressed with higher expression in heart, skeletal muscle and liver.
Cellular Localization: Cell membrane; Multi pass membrane protein
Storage: Store at -20C. Avoid freeze / thaw cycles.

Product Link: https://www.elabscience.com/p-abca8_polyclonal_antibody-26709.html
Manual Link: https://www.elabscience.com/viewpdf-26709-elabscience-E-AB-30384.PDF