Catalog No#: S-079-100
Product Name: Sheep antibody to human proBDNF: whole serum
Alternative Name: Proform brain derived neurotrophic factor
Product Type: Polyclonal Antibody
Description: Brain derived neurotrophic factor (BDNF) is synthesized as a precursor (proBDNF) which may be released and have physiological functions to cause cell death. It binds neurotrophin receptor p75 and sortilin and may also be important for the development of nervous system. proBDNF is synthesized in neurons and glia (eg., microglia), transported anterogradely and retrogradely and may be released in an activity dependent manner. This antibody is raised in sheep to detect the prodomain of BDNF and not the mature peptide.
Size: 100 uL
Applications: WB; ELISA; Neut, Neutralizing
Recommended Dilutions: ELISA, Western Blot, biological neutralization of proBDNF, Immunocytochemistry/Immunofluorescence. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
Immunogen: The recombinant prodomain fragment of human brain-derived neurotrophic factor
Purity: Whole Serum
Reconstitution: Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Species Reactivity: Human; Mouse; Rat
Specification: Confirmed to react with purified human proBDNF, crossreact with mouse and rat proBDNF | Cross reactivity with other species than human, mouse and rat has not yet been tested
Shipping Conditions: 25°C (Ambient)
Storage Conditions: After reconstitution keep aliquots at €“20 ºC for a higher stability, and at 4 ºC with an appropriate antibacterial agent. Glycerol (1:1) may be added for an additional stability. Avoid repetitive freeze/thaw cycles.
Expiration Date: 12 months after purchase
Datasheet Link: http://www.biosensis.com/pdf_datasheet.php?products_id=435
Product Link: http://www.biosensis.com/product_info.php/sheep-antibody-human-probdnf-whole-serum-p-435