Anti-CD5 Monoclonal Antibody
IHC538-100
Regular price
$165.00
Supplier: GenomeMe
Description:
Cluster of differentiation 5 (CD5) is expressed in high levels on the surface of T cells, while controversy surrounds the expression levels and role of CD5 in B cells. As a part of a diagnostic panel, its utility lies predominantly as a marker for T cells, with over 70% of T cell neoplasms expressing CD5. In particular, it is correlated with chronic lymphocytic leukemia/small lymphocytic lymphomas, mantle cell lymphoma, as well as a subset of diffuse large B cell lymphomas. CD5 demonstrates positive expression in thymic carcinomas, and is not as sensitive as CD3. CD5 also has value as a prognostic indicator, being associated with poor prognosis in acute T cell lymphoblastic leukemia.
| Clone | IHC538 |
| Source |
Mouse Monoclonal |
| Positive Control |
Tonsil, Lymph Node |
| Dilution Range | 1:100 - 1:400 |
Figure: GeneAbTM CD5 [IHC538] on Tonsil
References
- Mylonas I, et al. Anticancer Res. 2003; 23:1075-80.
- Fukazawa I, et al. Arch Gynecol Obstet. 1988; 243:41-50.
- Kabawat S, et al. Int J Gynecol Pathol. 1983; 2:275-285.
