Anti-p21 Monoclonal Antibody

Anti-p21 Monoclonal Antibody

IHC021-100

$60.00 You Pay

Supplier: GenomeMe

Description:

p21, also known as p21Cip1 , p21Waf1, cyclin-dependent kinase inhibitor 1, or CDK-interacting protein 1, functions to regulate cell cycle progression at G1 by inhibiting the activity of Cyclin-CDK2 or -CDK4 complexes. This cyclin-dependent kinase inhibitor is expressed in all adult human tissues, and decreased expression of p21 is linked to poor prognosis in a number of carcinomas including gastric carcinoma, non-small cell lung carcinoma and thyroid carcinoma. p21 is also associated with favourable prognosis in several tumors.

Specifications:

Clone IHC021
Source Mouse Monoclonal
Positive Control

Colon
Dilution Range 1:100 - 1:400

 

IFU & SDS:

Figure: GeneAbTM p21 [IHC021] on Small Intestine

References

  1. Arciniegas E, et al. Histol Histopathol. 2015; 30:453-63.
  2. Mino-Kenudson M, et al. Arch Pathol Lab Med. 2007; 131:86-90.
  3. Zhan XX, et al. Endocr Pathol. 2015; 26:21-6.
  4. Renaud F, et al. Thyroid. 2014; 24:1375-84.
  5. Kaira K, et al. Virchows Arch. 2011; 458:615-20.
  6. Hu XF, et al. Expert Rev Anticancer Ther. 2006; 6:1261-71
  7. Leroy X, et al. Ann Pathol. 2007; 26:257-66.
  8. Li Y, Cozzi PJ, Curr Cancer Drug Targets. 2007; 7:259-71.
  9. O’Connell FP, et al. Arch Pathol Lab Med. 2005; 129:338-47
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