Phospho-RUNX1 (Ser249) Polyclonal Antibody

Phospho-RUNX1 (Ser249) Polyclonal Antibody

E-AB-21010

Regular price $399.00 $349.00 You Pay

Supplier: Elabscience
Product Category: Phospho/Acetyl/Methyl
Description: Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well-documented and have been associated with several types of leukemia. Three transcript variants encoding different isoforms have been found for this gene
Research Areas: Cancer, Epigenetics and Nuclear Signaling, Developmental biology, Neuroscience, Stem cells
Size: 200 uL
Concentration: 1mg/mL
Applications: WB,ELISA
Recommended Dilutions: WB 1:500-1:2000, ELISA 1:5000
Clonality: Polyclonal
Clone No:
SwissProt: Q01196
Gene ID: 861
Reactivity: Human,Mouse,Rat
Host: Rabbit
Isotype: IgG
Immunogen: Synthesized peptide derived from human RUNX1 around the phosphorylation site of Ser249
Formulation: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Purification: Affinity purification
Conjugation: Unconjugated
Observed MW: 49kDa
Storage: Store at -20C. Avoid freeze / thaw cycles.
Cellular Localization: Nucleus.

Product Link: https://www.elabscience.com/p-phospho_runx1_(ser249)_polyclonal_antibody-25599.html
Manaul Link: https://www.elabscience.com/viewpdf-25599-elabscience-E-AB-21010.PDF