Phospho-SMAD2/3 (Thr8) Polyclonal Antibody

Supplier: Elabscience
Product Category: Phospho/Acetyl/Methyl
Description: SMAD is a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. They mediate the signal of the transforming growth factor (TGF)-beta, and thus regulate multiple cellular processes, such as cell proliferation, apoptosis, and differentiation.
Research Areas: Cancer, Epigenetics and Nuclear Signaling, Signal transduction, Stem cells
Size: 200 uL
Concentration: 1mg/mL
Applications: WB,ELISA
Recommended Dilutions: WB 1:500-1:2000, ELISA 1:10000
Clonality: Polyclonal
Clone No:
SwissProt: Q15796,P84022
Gene ID: 4087/4088
Reactivity: Human,Mouse,Rat
Host: Rabbit
Isotype: IgG
Immunogen: Synthesized peptide derived from human Smad2/3 around the phosphorylation site of Thr8
Formulation: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Purification: Affinity purification
Conjugation: Unconjugated
Observed MW: 48kDa
Storage: Store at -20C. Avoid freeze / thaw cycles.
Cellular Localization: Cytosol,Nucleus,heteromeric SMAD protein complex,nuclear chromatin,nuclear inner membrane,nucleoplasm,nucleus,Plasma Membrane,Other locations:cytoplasm,receptor complex,SMAD protein complex,transcription factor complex

Product Link: https://www.elabscience.com/p-phospho_smad2_3_(thr8)_polyclonal_antibody-25629.html
Manaul Link: https://www.elabscience.com/viewpdf-25629-elabscience-E-AB-21040.PDF