Phospho-RPA2 (Ser33) Polyclonal Antibody

Supplier: Elabscience
Product Category: Phospho/Acetyl/Methyl
Description: Replication protein A 32 kDa subunit is a protein that in humans is encoded by theRPA2 gene. As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.
Research Areas: Cancer, Epigenetics and Nuclear Signaling
Size: 200 uL
Concentration: 1mg/mL
Applications: WB,ELISA
Recommended Dilutions: WB 1:500-1:2000, ELISA 1:10000
Clonality: Polyclonal
Clone No:
SwissProt: P15927
Gene ID: 6118
Reactivity: Human,Mouse,Rat
Host: Rabbit
Isotype: IgG
Immunogen: Synthesized peptide derived from human RPA p32 around the phosphorylation site of Ser33
Formulation: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Purification: Affinity purification
Conjugation: Unconjugated
Observed MW: 32kDa
Storage: Store at -20C. Avoid freeze / thaw cycles.
Cellular Localization: Nucleus. Nucleus>PML body. Also present in PML nuclear bodies. Redistributes to discrete nuclear foci upon DNA damage.

Product Link: https://www.elabscience.com/p-phospho_rpa2_(ser33)_polyclonal_antibody-25669.html
Manaul Link: https://www.elabscience.com/viewpdf-25669-elabscience-E-AB-21080.PDF