Phospho-SNAI1 (Ser246) Polyclonal Antibody

Supplier: Elabscience
Product Category: Phospho/Acetyl/Methyl
Description: The Drosophila embryonic protein snail is a zinc finger transcriptional repressor which downregulates the expression of ectodermal genes within the mesoderm. The nuclear protein encoded by this gene is structurally similar to the Drosophila snail protein, and is also thought to be critical for mesoderm formation in the developing embryo. At least two variants of a similar processed pseudogene have been found on chromosome 2.
Research Areas: Cancer, Cardiovascular, Epigenetics and Nuclear Signaling
Size: 200 uL
Concentration: 1mg/mL
Applications: WB,IHC-p,IF,ELISA
Recommended Dilutions: WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:5000
Clonality: Polyclonal
Clone No:
SwissProt: O95863
Gene ID: 6615
Reactivity: Human,Mouse,Monkey
Host: Rabbit
Isotype: IgG
Immunogen: Synthesized peptide derived from human SNAI 1 around the phosphorylation site of Ser246
Formulation: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Purification: Affinity purification
Conjugation: Unconjugated
Observed MW: 29kDa
Storage: Store at -20C. Avoid freeze / thaw cycles.
Cellular Localization: Nucleus. Cytoplasm. Once phosphorylated (probably on Ser-107, Ser-111, Ser-115 and Ser-119) it is exported from the nucleus to the cytoplasm where subsequent phosphorylation of the destruction motif and ubiquitination involving BTRC occurs.

Product Link: https://www.elabscience.com/p-phospho_snai1_(ser246)_polyclonal_antibody-25707.html
Manaul Link: https://www.elabscience.com/viewpdf-25707-elabscience-E-AB-21118.PDF