Phospho-SYK (Tyr525) Polyclonal Antibody

Supplier: Elabscience
Product Category: Phospho/Acetyl/Methyl
Description: SYK(spleen tyrosine kinase) is a key regulator of signal transduction events,apoptosis and orderly cell cycle progression in B-lineage lymphoid cells. Although SYK has not been linked to a human disease, defective expression of the closely related T-cell tyrosine kinase ZAP-70 has been associated with severe combined immunodeficiency(PMID:11494125). This protein has 2 isoforms produced by alternative splicing.
Research Areas: Cancer, Cardiovascular, Immunology, Signal transduction
Size: 200 uL
Concentration: 1mg/mL
Applications: WB,IHC-p,ELISA
Recommended Dilutions: WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:20000
Clonality: Polyclonal
Clone No:
SwissProt: P43405
Gene ID: 6850
Reactivity: Human,Mouse,Rat,Monkey
Host: Rabbit
Isotype: IgG
Immunogen: Synthesized peptide derived from human Syk around the phosphorylation site of Tyr525
Formulation: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Purification: Affinity purification
Conjugation: Unconjugated
Observed MW: 72kDa
Storage: Store at -20C. Avoid freeze / thaw cycles.
Cellular Localization: Cell membrane. Cytoplasm, cytosol.

Product Link: https://www.elabscience.com/p-phospho_syk_(tyr525)_polyclonal_antibody-25744.html
Manaul Link: https://www.elabscience.com/viewpdf-25744-elabscience-E-AB-21155.PDF