Phospho-RPS6KA4 (Thr568) Polyclonal Antibody

Supplier: Elabscience
Product Category: Phospho/Acetyl/Methyl
Description: This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, including CREB1 and ATF1. The encoded protein can also phosphorylate histone H3 to regulate certain inflammatory genes. Several transcript variants encoding different isoforms have been found for this gene. RPS6KA4 (Ribosomal Protein S6 Kinase A4) is a Protein Coding gene. Among its related pathways are Type I Interferon Signaling Pathways and Endocytic Trafficking of EGFR. GO annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity. An important paralog of this gene is RPS6KA5.
Research Areas: Cancer, Signal transduction
Size: 200 uL
Concentration: 1mg/mL
Applications: WB,IHC-p,ELISA
Recommended Dilutions: WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:40000
Clonality: Polyclonal
Clone No:
SwissProt: O75676
Gene ID: 8986
Reactivity: Human,Mouse
Host: Rabbit
Isotype: IgG
Immunogen: Synthesized peptide derived from human MSK2 around the phosphorylation site of Thr568
Formulation: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Purification: Affinity purification
Conjugation: Unconjugated
Observed MW: 95kDa
Storage: Store at -20C. Avoid freeze / thaw cycles.
Cellular Localization: Nucleus.

Product Link: https://www.elabscience.com/p-phospho_rps6ka4_(thr568)_polyclonal_antibody-25820.html
Manaul Link: https://www.elabscience.com/viewpdf-25820-elabscience-E-AB-21231.PDF