Phospho-SNCA (Tyr125) Polyclonal Antibody

Supplier: Elabscience
Product Category: Phospho/Acetyl/Methyl
Description: Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Four alternatively spliced transcripts encoding two different isoforms have been identified for this gene.
Research Areas: Cancer, Neuroscience
Size: 200 uL
Concentration: 1mg/mL
Applications: WB,IHC-p,ELISA
Recommended Dilutions: IHC 1:100-1:300, ELISA 1:20000
Clonality: Polyclonal
Clone No:
SwissProt: P37840
Gene ID: 6622
Reactivity: Human,Mouse,Rat
Host: Rabbit
Isotype: IgG
Immunogen: Synthesized peptide derived from human Synuclein-? around the phosphorylation site of Y125.
Formulation: PBS with 0.02% sodium azide,0.5% BSA and 50% glycerol pH 7.4.
Purification: Affinity purification
Conjugation: Unconjugated
Observed MW:
Storage: Store at -20C. Avoid freeze / thaw cycles.
Cellular Localization: Cytoplasm, cytosol. Membrane. Nucleus. Cell junction, synapse. Secreted. Membrane-bound in dopaminergic neurons.

Product Link: https://www.elabscience.com/p-phospho_snca_(tyr125)_polyclonal_antibody-25889.html
Manaul Link: https://www.elabscience.com/viewpdf-25889-elabscience-E-AB-21300.PDF