Phospho-SF1 (Ser82) Polyclonal Antibody

Supplier: Elabscience
Product Category: Phospho/Acetyl/Methyl
Description: This gene encodes a nuclear pre-mRNA splicing factor. The encoded protein specifically recognizes the intron branch point sequence at the 3' splice site, together with the large subunit of U2 auxiliary factor (U2AF), and is required for the early stages of spliceosome assembly. It also plays a role in nuclear pre-mRNA retention and transcriptional repression. The encoded protein contains an N-terminal U2AF ligand motif, a central hnRNP K homology motif and quaking 2 region which bind a key branch-site adenosine within the branch point sequence, a zinc knuckles domain, and a C-terminal proline-rich domain. Alternative splicing results in multiple transcript variants.
Research Areas: Epigenetics and Nuclear Signaling
Size: 200 uL
Concentration: 1mg/mL
Applications: WB,IHC-p,IF,ELISA
Recommended Dilutions: WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:5000
Clonality: Polyclonal
Clone No:
SwissProt: Q15637
Gene ID: 7536
Reactivity: Human,Mouse,Monkey
Host: Rabbit
Isotype: IgG
Immunogen: Synthesized peptide derived from human Splicing factor 1 around the phosphorylation site of S82.
Formulation: PBS with 0.02% sodium azide,0.5% BSA and 50% glycerol pH 7.4.
Purification: Affinity purification
Conjugation: Unconjugated
Observed MW: 68kDa
Storage: Store at -20C. Avoid freeze / thaw cycles.
Cellular Localization: Nuclear

Product Link: https://www.elabscience.com/p-phospho_sf1_(ser82)_polyclonal_antibody-41834.html
Manaul Link: https://www.elabscience.com/viewpdf-41834-elabscience-E-AB-21962.PDF