Mouse Monoclonal Antibody to ANAPC10

Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: ANAPC10 is a core subunit of the anaphase-promoting complex (APC), or cyclosome, a ubiquitin protein ligase that is essential for progression through the cell cycle. APC initiates sister chromatid separation by ubiquitinating the anaphase inhibitor securin (PTTG1; MIM 604147) and triggers exit from mitosis by ubiquitinating cyclin B (CCNB1; MIM 123836), the activating subunit of cyclin-dependent kinase-1 (CDK1; MIM 116940) (summary by Wendt et al., 2001 [PubMed 11524682]).;
Application: ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000; ICC: 1/200 - 1/1000; FCM: 1/200 - 1/400
Size: 100 ul, 1mg/ml
Species Reactivity: Human
Clone: 8F1D10;
Isotype: Mouse IgG1
Immunogen: Purified recombinant fragment of human ANAPC10 (AA: 1-185) expressed in E. Coli.
Formulation: Purified antibody in PBS with 0.05% sodium azide
MW: 46.7kDa
Storage: 4C; -20C for long term storage
Supplier link: http://www.promab.com/index.php?main_page=product_info&products_id=4290
Reference: 1.BMC Cell Biol. 2004 May 16;5:20. ; 2.Nat Struct Biol. 2001 Sep;8(9):784-8.;

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