Mouse Monoclonal Antibody to IFN-gamma

Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: Interferon-? (IFN-?) is a pro-inflammatory cytokine that is central in host resistance to infection. It is mainly produced by natural killer cells and CD4+ and CD8+ T cells, its receptors are found on nearly all cells, where it activates diverse responses that enable potential host cells to prevent invasive infection by bacteria, parasites and viruses. Takayanagi et al. (2000) demonstrated that IFN-? strongly suppresses osteoclastogenesis by interfering with the RANKL (602642)-RANK (603499) signaling pathway. Tsubota et al. (1999) reported that this upregulation in Sjogren syndrome patients may be controlled by interferon-gamma through the activation of transcription factor NFKB
Application: ELISA: 1/10000; WB: 1/500 - 1/2000
Size: 100 ul, 1mg/ml
Species Reactivity: Human
Clone: 3F1E3;
Isotype: Mouse IgG1
Immunogen: Purified recombinant fragment of human IFN-? expressed in E. Coli.
Formulation: Purified antibody in PBS containing 0.03% sodium azide.
MW: 19.3kDa
Storage: 4C; -20C for long term storage
Supplier link: http://www.promab.com/index.php?main_page=product_info&products_id=40
Reference: 1. Takayanagi, H. et al. Nature 2000. 408: 600-605. ; 2. Tsubota, K. et al. Invest. Ophthal. Vis. Sci. 40: 28-34, 1999.

Note: Highly recommend to send quote request for product availability and estimated shipping charge