Mouse Monoclonal Antibody to Calcyclin

Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: Calcyclin encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-dependent insulin release, stimulation of prolactin secretion, and exocytosis. Chromosomal rearrangements and altered expression of this gene have been implicated in melanoma.
Application: ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000
Size: 100 ul, 1mg/ml
Species Reactivity: Human
Clone: 7D11;
Isotype: Mouse IgG1
Immunogen: Purified recombinant fragment of calcyclin expressed in E. Coli.
Formulation: Purified antibody in PBS containing 0.03% sodium azide.
MW: N/A
Storage: 4C; -20C for long term storage
Supplier link: http://www.promab.com/index.php?main_page=product_info&products_id=79
Reference: 1. Bean C.et.al J Mol Biol. 2005 Jun 3;349(2):349-66. ; 2. HWang R.et.al J Biol Chem. 2004 May 14;279(20):21239-47. ;

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