Mouse Monoclonal Antibody to LSD1/AOF220055
Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: The amine oxidase domain 2 (AOF2) gene encodes a nuclear protein (LSD1, ~95kDa) containing a Swirm domain, a FAD-binding motif, and an amine oxidase domain. This protein is a component of several histone deacetylase complexes, though it silences genes by functioning as a histone demethylase. LSD1 is a chromatin-modifying enzyme, which serve as a docking module for the stabilization of the associated corepressor complex (es) on chromatin.
Application: ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000
Size: 100 ul, 1mg/ml
Species Reactivity: Human; Mouse; Monkey
Isotype: Mouse IgG1
Immunogen: Purified recombinant fragment of human LSD1 expressed in E. Coli.
Formulation: Ascitic fluid containing 0.03% sodium azide.
Storage: 4C; -20C for long term storage
Supplier link: http://www.promab.com/index.php?main_page=product_info&products_id=80
Reference: 1. Shi YJ, et.al Mol Cell. 2005 Sep 16;19(6):857-64. ; 2. Metzger E, et.al Nature. 2005 Sep 15;437(7057):436-9. ;
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