Mouse Monoclonal Antibody to IGFBP220204
Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: IGFBP2: insulin-like growth factor binding protein 2. IGFBP2 is a member of the ISGBP family which bind various IGFs. IGFBP2 is overexpressed in a wide spectrum of other cancers, including glioma, prostate cancer, synovial sarcoma, neuroblastoma, colon cancer, adrenocortical cancer, lung cancer, Wilms' tumor, and hepatoblastoma. The overexpression of IGFBP2 also correlates with the aggressiveness of some tumors. IGFBP2 activates the expression of matrix metalloprotease 2, which contributes to cell invasiveness.
Application: ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000
Size: 100 ul, 1mg/ml
Species Reactivity: Human
Isotype: Mouse IgG1
Immunogen: Purified recombinant fragment of protein IGFBP2 (aa180-328) expressed in E. Coli. ;
Formulation: Ascitic fluid containing 0.03% sodium azide.
Storage: 4C; -20C for long term storage
Supplier link: http://www.promab.com/index.php?main_page=product_info&products_id=209
Reference: 1. Oncol Rep. 2005 Feb;13(2):341-5. ; 2. Prostate. 2005 Jun 15;64(1):9-19. ; 3. Bone. 2005 Dec;37(6):741-50.
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