Mouse Monoclonal Antibody to CD18

Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: CD18, also known as ITGB2 (integrin beta chain beta 2). Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. For example, beta 2 combines with the alpha L chain to form the integrin LFA-1, and combines with the alpha M chain to form the integrin Mac-1. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. CD18 is expressed by most leucocytes. Defects in this gene are the cause of leukocyte adhesion deficiency type I (LAD1). Two transcript variants encoding the same protein have been identified for this gene.
Application: ELISA: 1/10000; ICC: 1/200 - 1/1000
Size: 100 ul, 1mg/ml
Species Reactivity: Human, Mouse
Clone: 10E12;
Isotype: Mouse IgG2b
Immunogen: Purified recombinant fragment of CD18 expressed in E. Coli.
Formulation: Ascitic fluid containing 0.03% sodium azide.
MW: 85kDa
Storage: 4C; -20C for long term storage
Supplier link: http://www.promab.com/index.php?main_page=product_info&products_id=326
Reference: 1. Microcirculation. 2008 Aug;15(6):555-67. ; 2. Mol Immunol. 2008 Feb;45(3):709-18. ; 3. J Biol Chem. 2007 Aug 17;282(33):24310-9.

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