Mouse Monoclonal Antibody to JAK3

Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: JAK3, Janus kinase 3. It is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease).
Application: ELISA: 1/10000; WB: 1/500 - 1/2000; ICC: 1/200 - 1/1000; FCM: 1/200 - 1/400
Size: 100 ul, 1mg/ml
Species Reactivity: Human; Mouse
Clone: 5H2;
Isotype: Mouse IgG1
Immunogen: Purified recombinant fragment of human JAK3 expressed in E. Coli.
Formulation: Ascitic fluid containing 0.03% sodium azide.
MW: 125kDa
Storage: 4C; -20C for long term storage
Supplier link: http://www.promab.com/index.php?main_page=product_info&products_id=370
Reference: 1. J Biol Chem. 1995 Oct 20;270(42):25028-36. ; 2. Proc Natl Acad Sci U S A. 1994 Jul 5;91(14):6374-8. ; 3. Leuk Lymphoma. 2002 Dec;43(12):2355-62. ;

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