Figure 1: Western blot analysis using HEXA mAb against human HEXA (AA: 29-181) recombinant protein. (Expected MW is 43.1 kDa)
Mouse Monoclonal Antibody to HEXA

Mouse Monoclonal Antibody to HEXA

30343

Regular price $341.00 $290.00 You Pay

Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: This gene encodes the alpha subunit of the lysosomal enzyme beta-hexosaminidase that, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Beta-hexosaminidase is composed of two subunits, alpha and beta, which are encoded by separate genes. Both beta-hexosaminidase alpha and beta subunits are members of family 20 of glycosyl hydrolases. Mutations in the alpha or beta subunit genes lead to an accumulation of GM2 ganglioside in neurons and neurodegenerative disorders termed the GM2 gangliosidoses. Alpha subunit gene mutations lead to Tay-Sachs disease (GM2-gangliosidosis type I).
Application: ELISA: 1/10000; WB: 1/500 - 1/2000; FCM: 1/200 - 1/400
Size: 100 ul, 1mg/ml
Species Reactivity: Human
Clone: 3F10;
Isotype: Mouse IgG2b
Immunogen: Purified recombinant fragment of human HEXA expressed in E. Coli. ;
Formulation: Purified antibody in PBS with 0.05% sodium azide
MW: 60.7kDa
Storage: 4C; -20C for long term storage
Spplier link: http://www.promab.com/index.php?main_page=product_info&products_id=742
Reference: Clin Biochem. 2009 Jul;42(10-11):1187-9. ; Pediatr Res. 2010 Feb;67(2):217-20. ;