Mouse Monoclonal Antibody to MRPL42

Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a protein identified as belonging to both the 28S and the 39S subunits. Alternative splicing results in multiple transcript variants. Pseudogenes corresponding to this gene are found on chromosomes 4q, 6p, 6q, 7p, and 15q. ; ;
Application: ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000; ICC: 1/300; FCM: 1/200 - 1/400
Size: 100 ul, 1mg/ml
Species Reactivity: Human
Clone: 3H6G11;
Isotype: Mouse IgG1
Immunogen: Purified recombinant fragment of human MRPL42 (AA: 142-203) expressed in E. Coli.
Formulation: Purified antibody in PBS with 0.05% sodium azide
MW: 16.7kDa
Storage: 4C; -20C for long term storage
Supplier link: http://www.promab.com/index.php?main_page=product_info&products_id=915
Reference: 1.J Biol Chem. 2001 Nov 23;276(47):43958-69. ; 2.Genomics. 2003 May;81(5):468-80. ;

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