Mouse Monoclonal Antibody to MCAM
30560
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$341.00
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Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: The protein encoded by this gene plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during ; embryonic development. Acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2/FAK1, and a transient increase in the intracellular calcium concentration ;
Application: ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000
Size: 100 ul, 1mg/ml
Species Reactivity: Human
Clone: 6C3F1;
Isotype: Mouse IgG1
Immunogen: Purified recombinant fragment of human MCAM (AA: 84-189) expressed in E. Coli.
Formulation: Purified antibody in PBS with 0.05% sodium azide
MW: 71.6kDa
Storage: 4C; -20C for long term storage
Supplier link: http://www.promab.com/index.php?main_page=product_info&products_id=3521
Reference: 1. Cancer Lett. 2013 Apr 28;330(2):150-62. ; 2. J Biol Chem. 2013 Jan 25;288(4):2571-9. ;
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