Mouse Monoclonal Antibody to TIE130619
Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: This gene encodes a member of the tyrosine protein kinase family. The encoded protein plays a critical role in angiogenesis and blood vessel stability by inhibiting angiopoietin 1 signaling through the endothelial receptor tyrosine kinase Tie2. Ectodomain cleavage of the encoded protein relieves inhibition of Tie2 and is mediated by multiple factors including vascular endothelial growth factor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. ;
Application: ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000
Size: 100 ul, 1mg/ml
Species Reactivity: Human
Isotype: Mouse IgG1
Immunogen: Purified recombinant fragment of human TIE1 (AA: 385-607) expressed in E. Coli.
Formulation: Purified antibody in PBS with 0.05% sodium azide.
Storage: 4C; -20C for long term storage
Supplier link: http://www.promab.com/index.php?main_page=product_info&products_id=3580
Reference: 1. Int J Oncol. 2007 Oct;31(4):893-7. ; 2. Cancer. 2002 Mar 1;94(5):1517-21. ;
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