Mouse Monoclonal Antibody to CAV2

Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: The protein encoded by this gene is a major component of the inner surface of caveolae, small invaginations of the plasma membrane, and is involved in essential cellular functions, including signal transduction, lipid metabolism, cellular growth control and apoptosis. This protein may function as a tumor suppressor. This gene and related family member (CAV1) are located next to each other on chromosome 7, and express colocalizing proteins that form a stable hetero-oligomeric complex. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. Additional isoforms resulting from the use of alternate in-frame translation initiation codons have also been described, and shown to have preferential localization in the cell (PMID:11238462).
Application: ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000; FCM: 1/200 - 1/400
Size: 100 ul, 1mg/ml
Species Reactivity: Human
Clone: 5E9E2;
Isotype: Mouse IgG1
Immunogen: Purified recombinant fragment of human CAV2 (AA: 1-86) expressed in E. Coli.
Formulation: Purified antibody in PBS with 0.05% sodium azide.
MW: 18.3kDa
Storage: 4C; -20C for long term storage
Supplier link: http://www.promab.com/index.php?main_page=product_info&products_id=3606
Reference: 1. Int J Oncol. 2011 May;38(5):1395-402.; 2. Breast Cancer Res Treat. 2008 Jul;110(2):245-56.

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