Mouse Monoclonal Antibody to XRCC630686
Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus.
Application: ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000; ICC: 1/200 - 1/1000; FCM: 1/200 - 1/400
Size: 100 ul, 1mg/ml
Species Reactivity: Human
Isotype: Mouse IgG1
Immunogen: Purified recombinant fragment of human XRCC6 (AA: 6-214) expressed in E. Coli.
Formulation: Purified antibody in PBS with 0.05% sodium azide.
Storage: 4C; -20C for long term storage
Supplier link: http://www.promab.com/index.php?main_page=product_info&products_id=3647
Reference: 1. Clin Cancer Res. 2013 Mar 15;19(6):1547-56.; 2. Mol Carcinog. 2012 Oct;51 Suppl 1:E183-90.
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