Mouse Monoclonal Antibody to PLCG2

Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: The protein encoded by this gene is a transmembrane signaling enzyme that catalyzes the conversion of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate to 1D-myo-inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG) using calcium as a cofactor. IP3 and DAG are second messenger molecules important for transmitting signals from growth factor receptors and immune system receptors across the cell membrane. Mutations in this gene have been found in autoinflammation, antibody deficiency, and immune dysregulation syndrome and familial cold autoinflammatory syndrome 3.;
Application: ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000; ICC: ; FCM:
Size: 100 ul, 1mg/ml
Species Reactivity: Human
Clone: 1E10C11;
Isotype: Mouse IgG1
Immunogen: Purified recombinant fragment of human PLCG2 (AA: 826-985) expressed in E. Coli.
Formulation: Purified antibody in PBS with 0.05% sodium azide
MW: 147.9kDa
Storage: 4C; -20C for long term storage
Supplier link: http://www.promab.com/index.php?main_page=product_info&products_id=3953
Reference: 1.J Biol Chem. 2005 Nov 25;280(47):38923-31. ; 2.World J Gastroenterol. 2003 Nov;9(11):2413-8.;

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