Mouse Monoclonal Antibody to Neuropilin-1

Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: This gene encodes one of two neuropilins, which contain specific protein domains which allow them to participate in several different types of signaling pathways that control cell migration. Neuropilins contain a large N-terminal extracellular domain, made up of complement-binding, coagulation factor V/VIII, and meprin domains. These proteins also contains a short membrane-spanning domain and a small cytoplasmic domain. Neuropilins bind many ligands and various types of co-receptors; they affect cell survival, migration, and attraction. Some of the ligands and co-receptors bound by neuropilins are vascular endothelial growth factor (VEGF) and semaphorin family members. Several alternatively spliced transcript variants that encode different protein isoforms have been described for this gene.;
Application: ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: ; ICC: ; FCM: 1/200 - 1/400
Size: 100 ul, 1mg/ml
Species Reactivity: Human
Clone: 5B1E11;
Isotype: Mouse IgG1
Immunogen: Synthesized peptide of human Neuropilin-1 (AA: 45-59).
Formulation: Purified antibody in PBS with 0.05% sodium azide
MW: 103.1kDa
Storage: 4C; -20C for long term storage
Supplier link: http://www.promab.com/index.php?main_page=product_info&products_id=3973
Reference: 1.Leuk Res. 2012 Feb;36(2):169-73. ; 2.Blood. 2011 Jan 20;117(3):920-7.;

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