Mouse Monoclonal Antibody to PPARA

Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: Peroxisome proliferators include hypolipidemic drugs, herbicides, leukotriene antagonists, and plasticizers; this term arises because they induce an increase in the size and number of peroxisomes. Peroxisomes are subcellular organelles found in plants and animals that contain enzymes for respiration and for cholesterol and lipid metabolism. The action of peroxisome proliferators is thought to be mediated via specific receptors, called PPARs, which belong to the steroid hormone receptor superfamily. PPARs affect the expression of target genes involved in cell proliferation, cell differentiation and in immune and inflammation responses. Three closely related subtypes (alpha, beta/delta, and gamma) have been identified. This gene encodes the subtype PPAR-alpha, which is a nuclear transcription factor. Multiple alternatively spliced transcript variants have been described for this gene, although the full-length nature of only two has been determined. ;
Application: ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: ; ICC: ; FCM: 1/200 - 1/400
Size: 100 ul, 1mg/ml
Species Reactivity: Human
Clone: 5D10E10;
Isotype: Mouse IgG1
Immunogen: Purified recombinant fragment of human PPARA (AA: 1-120) expressed in E. Coli.
Formulation: Purified antibody in PBS with 0.05% sodium azide
MW: 52.2kDa
Storage: 4C; -20C for long term storage
Supplier link: http://www.promab.com/index.php?main_page=product_info&products_id=4006
Reference: 1.Blood. 2013 Aug 8;122(6):969-80. ; 2.Leukemia. 2013 Apr;27(5):1090-9.;

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