Mouse Monoclonal Antibody to DDX39B

Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: This gene encodes a member of the DEAD box family of RNA-dependent ATPases that mediate ATP hydrolysis during pre-mRNA splicing. The encoded protein is an essential splicing factor required for association of U2 small nuclear ribonucleoprotein with pre-mRNA, and it also plays an important role in mRNA export from the nucleus to the cytoplasm. This gene belongs to a cluster of genes localized in the vicinity of the genes encoding tumor necrosis factor alpha and tumor necrosis factor beta. These genes are all within the human major histocompatibility complex class III region. Mutations in this gene may be associated with rheumatoid arthritis. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on both chromosomes 6 and 11. Read-through transcription also occurs between this gene and the upstream ATP6V1G2 (ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2) gene.;
Application: ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000; ICC: 1/200 - 1/1000; FCM:
Size: 100 ul, 1mg/ml
Species Reactivity: Human; Mouse
Clone: 2F5G7;
Isotype: Mouse IgG1
Immunogen: Purified recombinant fragment of human DDX39B (AA: 1-250) expressed in E. Coli.
Formulation: Purified antibody in PBS with 0.05% sodium azide
MW: 49kDa
Storage: 4C; -20C for long term storage
Supplier link: http://www.promab.com/index.php?main_page=product_info&products_id=4015
Reference: 1.J Virol. 2011 Sep;85(17):8646-55. ; 2.Biochem Biophys Res Commun. 2010 Feb 26;393(1):106-10.;

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