Mouse Monoclonal Antibody to SK2

Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: This gene encodes one of two sphingosine kinase isozymes that catalyze the phosphorylation of sphingosine into sphingosine 1-phosphate. Sphingosine 1-phosphate mediates many cellular processes including migration, proliferation and apoptosis, and also plays a role in several types of cancer by promoting angiogenesis and tumorigenesis. The encoded protein may play a role in breast cancer proliferation and chemoresistance. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.;
Application: ELISA: 1/10000; WB: ; IHC: 1/200 - 1/1000; ICC: 1/200 - 1/1000; FCM: 1/200 - 1/400
Size: 100 ul, 1mg/ml
Species Reactivity: Human
Clone: 3C8D3;
Isotype: Mouse IgG1
Immunogen: Synthesized peptide of human SK2 (AA: 36-52).
Formulation: Purified antibody in PBS with 0.05% sodium azide
MW: 69.2kDa
Storage: 4C; -20C for long term storage
Supplier link: http://www.promab.com/index.php?main_page=product_info&products_id=4036
Reference: 1.Tumour Biol. 2014 Jan;35(1):363-8. ; 2.Electrophoresis. 2011 Jun;32(13):1742-9. ;

Note: Highly recommend to send quote reqeust for estimated shipping charge including ice