Mouse Monoclonal Antibody to GRM531260
Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: This gene encodes a member of the G-protein coupled receptor 3 protein family. The encoded protein is a metabatropic glutamate receptor, whose signaling activates a phosphatidylinositol-calcium second messenger system. This protein may be involved in the regulation of neural network activity and synaptic plasticity. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. A pseudogene of this gene has been defined on chromosome 11. Alternative splicing results in multiple transcript variants.
Application: ELISA: 1/10000; WB: 1/500 - 1/2000; ICC: N/A; FCM: N/A; IHC: N/A
Size: 100 ul, 1mg/ml
Species Reactivity: Human
Isotype: Mouse IgG1
Immunogen: Purified recombinant fragment of human GRM5 (AA: extra 458-580) expressed in E. Coli.
Formulation: Purified antibody in PBS with 0.05% sodium azide
Storage: 4C; -20C for long term storage
Supplier link: http://www.promab.com/index.php?main_page=product_info&products_id=4410
Reference: 1.Curr Alzheimer Res. 2014;11(7):694-705.2.Int J Neuropsychopharmacol. 2014 Dec;17(12):1915-22.
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