Mouse Monoclonal Antibody to BCL2L2

Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: This gene encodes a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators. Expression of this gene in cells has been shown to contribute to reduced cell apoptosis under cytotoxic conditions. Studies of the related gene in mice indicated a role in the survival of NGF- and BDNF-dependent neurons. Mutation and knockout studies of the mouse gene demonstrated an essential role in adult spermatogenesis. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream PABPN1 (poly(A) binding protein, nuclear 1) gene.
Application: ELISA: 1/10000; WB: 1/500 - 1/2000; ICC: N/A; FCM: 1/200 - 1/400; IHC: N/A
Size: 100 ul, 1mg/ml
Species Reactivity: Human
Clone: 4G12D11
Isotype: Mouse IgG2a
Immunogen: Purified recombinant fragment of human BCL2L2 (AA: 6-118) expressed in E. Coli.
Formulation: Purified antibody in PBS with 0.05% sodium azide
MW: 20.7kDa
Storage: 4C; -20C for long term storage
Supplier link: http://www.promab.com/index.php?main_page=product_info&products_id=4423
Reference: 1.J Mol Biol. 2014 Jun 12;426(12):2346-62.2.Zhonghua Zhong Liu Za Zhi. 2012 Mar;34(3):182-6.

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