Mouse Monoclonal Antibody to ALDOA

Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: The protein encoded by this gene, Aldolase A (fructose-bisphosphate aldolase), is a glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Three aldolase isozymes (A, B, and C), encoded by three different genes, are differentially expressed during development. Aldolase A is found in the developing embryo and is produced in even greater amounts in adult muscle. Aldolase A expression is repressed in adult liver, kidney and intestine and similar to aldolase C levels in brain and other nervous tissue. Aldolase A deficiency has been associated with myopathy and hemolytic anemia. Alternative splicing and alternative promoter usage results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 3 and 10.
Application: ELISA: 1/10000; WB: 1/500 - 1/2000; ICC: N/A; FCM: 1/200 - 1/400; IHC: 1/200 - 1/1000
Size: 100 ul, 1mg/ml
Species Reactivity: Human;Mouse
Clone: 1C5B2
Isotype: Mouse IgG2a
Immunogen: Purified recombinant fragment of human ALDOA (AA: 9-145) expressed in E. Coli.
Formulation: Purified antibody in PBS with 0.05% sodium azide
MW: 39.4kDa
Storage: 4C; -20C for long term storage
Supplier link: http://www.promab.com/index.php?main_page=product_info&products_id=4437
Reference: 1.Cancer Lett. 2016 Apr 28;374(1):127-35. 2.Oncol Rep. 2014 Nov;32(5):2031-7.

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