Mouse Monoclonal Antibody to TNFRSF11A

Supplier: ProMab Technologies
Type of Product: Monoclonal
Description: The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptors can interact with various TRAF family proteins, through which this receptor induces the activation of NF-kappa B and MAPK8/JNK. This receptor and its ligand are important regulators of the interaction between T cells and dendritic cells. This receptor is also an essential mediator for osteoclast and lymph node development. Mutations at this locus have been associated with familial expansile osteolysis, autosomal recessive osteopetrosis, and Paget disease of bone. Alternatively spliced transcript variants have been described for this locus.
Application: ELISA: 1/10000; WB: 1/500 - 1/2000; ICC: N/A; FCM: 1/200 - 1/400; IHC: N/A
Size: 100 ul, 1mg/ml
Species Reactivity: Human
Clone: 8H8B2
Isotype: Mouse IgG1
Immunogen: Purified recombinant fragment of human TNFRSF11A (AA: extra 30-212) expressed in E. Coli.
Formulation: Purified antibody in PBS with 0.05% sodium azide
MW: 66kDa
Storage: 4C; -20C for long term storage
Supplier link: http://www.promab.com/index.php?main_page=product_info&products_id=4625
Reference: 1.Anticancer Res. 2016 Mar;36(3):1127-34.2.Int J Clin Exp Pathol. 2015 Feb 1;8(2):2249-58.

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