Mouse Monoclonal Antibody to LILRB2

Supplier: ProMab Technologies
Type of Product: Monoclonal
Description: This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene.
Application: ELISA: 1/10000; WB: 1/500 - 1/2000; ICC: N/A; FCM: 1/200 - 1/400; IHC: N/A
Size: 100 ul, 1mg/ml
Species Reactivity: Human
Clone: 2G7E11
Isotype: Mouse IgG2a
Immunogen: Purified recombinant fragment of human LILRB2 (AA: 51-184) expressed in E. Coli.
Formulation: Purified antibody in PBS with 0.05% sodium azide
MW: 65kDa
Storage: 4C; -20C for long term storage
Supplier link: http://www.promab.com/index.php?main_page=product_info&products_id=4627
Reference: 1.J Immunol Res. 2016;2016:4163094.2.PLoS One. 2014 Mar 27;9(3):e92018.

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