Mouse Monoclonal Antibody to TNFRSF18

Supplier: ProMab Technologies
Type of Product: Monoclonal
Description: This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
Application: ELISA: 1/10000; WB: 1/500 - 1/2000; ICC: N/A; FCM: 1/200 - 1/400; IHC: 1/200 - 1/1000
Size: 100 ul, 1mg/ml
Species Reactivity: Human
Clone: 4H2D6
Isotype: Mouse IgG1
Immunogen: Purified recombinant fragment of human TNFRSF18 (AA: extra 26-162) expressed in E. Coli.
Formulation: Purified antibody in PBS with 0.05% sodium azide
MW: 26kDa
Storage: 4C; -20C for long term storage
Supplier link: http://www.promab.com/index.php?main_page=product_info&products_id=4637
Reference: 1.Immunol Lett. 2014 Dec;162(2 Pt B):210-6.2.Int J Rheum Dis. 2016 Feb;19(2):199-204.

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