Mouse Monoclonal Antibody to TIM3

Supplier: ProMab Technologies
Type of Product: Monoclonal
Description: The protein encoded by this gene belongs to the immunoglobulin superfamily, and TIM family of proteins. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas, Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. This protein is a Th1-specific cell surface protein that regulates macrophage activation, and inhibits Th1-mediated auto- and alloimmune responses, and promotes immunological tolerance.
Application: ELISA: 1/10000; WB: 1/500 - 1/2000; ICC: N/A; FCM: 1/200 - 1/400; IHC: N/A
Size: 100 ul, 1mg/ml
Species Reactivity: Human
Clone: 2A7A6
Isotype: Mouse IgG1
Immunogen: Purified recombinant fragment of human TIM3 (AA: 224-301) expressed in E. Coli.
Formulation: Purified antibody in PBS with 0.05% sodium azide
MW: 33.4kDa
Storage: 4C; -20C for long term storage
Supplier link: http://www.promab.com/index.php?main_page=product_info&products_id=4638
Reference: 1.Tumour Biol. 2016 Jun;37(6):8209-18.2.Int Immunopharmacol. 2015 Dec;29(2):635-641.

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