Mouse Monoclonal Antibody to AUP1

Supplier: ProMab Technologies
Type of Product: Monoclonal
Description: The protein encoded this gene is involved in several pathways including quality control of misfolded proteins in the endoplasmic reticulum and lipid droplet accumulation. Lipid droplets are organelles in the cytoplasm that store neutral lipids such as cholesterol esters and trigylycerides to prevent the overabundance of free cholesterol and fatty acids in cells, but also to act as storage for other metabolic processes, such as membrane biogenesis. Reduced expression of this gene results in reduced lipid droplet clustering, a function that is dependent on ubiquitination of the protein. This protein contains multiple domains including a hydrophobic N-terminal domain, an acetyltranferase domain, a ubiquitin-binding CUE domain, and a UBE2B2-binding domain (G2BR). Alternative splicing results in multiple transcript variants.
Application: ELISA: 1/10000; WB: 1/500 - 1/2000; ICC: N/A; FCM: N/A; IHC: N/A
Size: 100 ul, 1mg/ml
Species Reactivity: Human;Mouse
Clone: 1H6A1
Isotype: Mouse IgG2b
Immunogen: Purified recombinant fragment of human AUP1 (AA: 229-410) expressed in E. Coli.
Formulation: Purified antibody in PBS with 0.05% sodium azide
MW: 53kDa
Storage: 4C; -20C for long term storage
Supplier link: http://www.promab.com/index.php?main_page=product_info&products_id=4639
Reference: 1.J Lipid Res. 2013 Feb;54(2):503-13.2.J Biol Chem. 2011 Feb 18;286(7):5599-606.

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