Anti-Oct-4 Monoclonal Antibody

Anti-Oct-4 Monoclonal Antibody

IHC643-100

$80.00 You Pay

Supplier: GenomeMe

Description:

Octamer-binding transcription factor 4 (Oct-4), also known as POU5F1 (POU domain, class 5, transcription factor 1), is a member of the POU homeodomain family of transcription factors and is involved in the maintenance and regulation of pluripotency in embryonic stem and germ cells. Anti-Oct-4 is highly useful and sensitive for seminomas, germinoma, dysgerminoma, embryonal carcinoma, and gonadoblastoma. Oct-4 may be associated with tumorigenesis, and can have an effect on some aspects of tumor behavior, including tumor recurrence or resistance to therapies.

Specifications:

Clone IHC643
Source Mouse Monoclonal
Positive Control

Seminoma
Dilution Range 1:100 - 1:400

IFU & SDS:

Figure: GeneAbTM   Oct-4 [IHC643] on GallBladder

References

  1. Baker PM, et al. Int J Gynecol Pathol. 2005; 24:39-55.
  2. Biermann K, et al. Histopathology. 2006; 49:290-7.
  3. Cheng CJ, et al. J Biomed Sci. 2007; 14:797-807.
  4. Cools M, et al. J Clin Endocrinol Metab. 2006; 91:2404-13.
  5. Niwa H, et al. Nat Genet. 2000; 24:372-6.
  6. Biermann K, et al. Histopathology. 2006; 49:290-7.
  7. Cheng L, et al. J Pathol. 2007; 211:1-9.
  8. Linn DE, et al. Genes Cancer. 2010; 1:908-16.