APLP1 Polyclonal Antibody

Supplier: Elabscience
Product Type: Antibody
Clonality: Polyclonal
Descritpion: This gene encodes a member of the highly conserved amyloid precursor protein gene family. The encoded protein is a membrane-associated glycoprotein that is cleaved by secretases in a manner similar to amyloid beta A4 precursor protein cleavage. This cleavage liberates an intracellular cytoplasmic fragment that may act as a transcriptional activator. The encoded protein may also play a role in synaptic maturation during cortical development. Alternatively spliced transcript variants encoding different isoforms have been described.

Research Areas: Neuroscience
Applications: WB,IHC,ELISA
Recommended Dilutions: WB 1:500-1:2000, IHC 1:25-1:100
Size: 200 uL
Concentration: 0.3mg/mL
Swissprot: P51693
Gene Accession: BC012889
Reactivity: Human,Mouse
Host: Rabbit
Isotype: IgG
Immunogen: Recombinant protein of human APLP1
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Conjugation: Unconjugated
Calculated MW: 72kDa
Tissue Specificity/Positive Control: Expressed in the cerebral cortex where it is localized to the postsynaptic density (PSD).
Cellular Localization: Cell membrane and Cytoplasm. C-terminally processed in the Golgi complex.
Storage: Store at -20C. Avoid freeze / thaw cycles.

Product Link: https://www.elabscience.com/p-aplp1_polyclonal_antibody-30106.html
Manual Link: https://www.elabscience.com/viewpdf-30106-elabscience-E-AB-10047.PDF