SPTLC1 Polyclonal Antibody

Supplier: Elabscience
Product Type: Antibody
Clonality: Polyclonal
Descritpion: This gene encodes a member of the class-II pyridoxal-phosphate-dependent aminotransferase family. The encoded protein is the long chain base subunit 1 of serine palmitoyltransferase. Serine palmitoyltransferase converts L-serine and palmitoyl-CoA to 3-oxosphinganine with pyridoxal 5'-phosphate and is the key enzyme in sphingolipid biosynthesis. Mutations in this gene were identified in patients with hereditary sensory neuropathy type 1. Alternatively spliced variants encoding different isoforms have been identified. Pseudogenes of this gene have been defined on chromosomes 1, 6, 10, and 13.
Research Areas: Cancer, Cardiovascular, Metabolism, Neuroscience, Signal transduction
Applications: WB,IHC,ELISA
Recommended Dilutions: WB 1:200-1:1000, IHC 1:25-1:100
Size: 200 uL
Concentration: 0.1mg/mL
Swissprot: O15269
Gene Accession: BC068537
Reactivity: Human
Host: Rabbit
Isotype: IgG
Immunogen: Recombinant protein of human SPTLC1
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Conjugation: Unconjugated
Calculated MW: 53kDa
Tissue Specificity/Positive Control: Widely expressed. Not detected in small intestine.
Cellular Localization: Endoplasmic reticulum membrane.
Storage: Store at -20C. Avoid freeze / thaw cycles.

Product Link: https://www.elabscience.com/p-sptlc1_polyclonal_antibody-30928.html
Manual Link: https://www.elabscience.com/viewpdf-30928-elabscience-E-AB-10884.PDF