Product Type: Antibody
Descritpion: The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. The encoded protein is a member of the proteasome B-type family, also known as the T1B family, and is a 20S core beta subunit in the proteasome. Expression of this catalytic subunit is downregulated by gamma interferon, and proteolytic processing is required to generate a mature subunit. A pseudogene of this gene is located on the long arm of chromosome 14.
Research Areas: Cancer, Cell Biology
Recommended Dilutions: WB 1:500-1:2000, IHC 1:25-1:100
Size: 200 uL
Gene Accession: BC000509
Immunogen: Recombinant protein of human PSMB7
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Calculated MW: 30kDa
Tissue Specificity/Positive Control: Expressed at a low level in colonic mucosa. Up-regulated in colorectal cancer tissues.
Cellular Localization: Cytoplasm. Nucleus.
Storage: Store at -20C. Avoid freeze / thaw cycles.
Product Link: https://www.elabscience.com/p-psmb7_polyclonal_antibody-30932.html
Manual Link: https://www.elabscience.com/viewpdf-30932-elabscience-E-AB-10888.PDF