CCDC106 Polyclonal Antibody

Supplier: Elabscience
Product Type: Antibody
Clonality: Polyclonal
Descritpion: The coiled-coil domain is a common protein motif that is often involved in protein oligomerization and is found in proteins such as transcription factors and intermediate filaments. CCDC106 was initially identified as a p53-interacting protein by yeast two-hybrid screening. Other experiments demonstrated that CCDC106 co-localizes and interacts with p53 in the nucleus, inhibiting the transcriptional activity of p53 and stimulating p53 protein degradation, indicating that at least one of the functions of CCDC106 is acting as a negative regulator of p53.
Research Areas: Cancer
Applications: IHC,ELISA
Recommended Dilutions: IHC 1:100-1:300
Size: 200 uL
Concentration: 0.3mg/mL
Swissprot: Q9BWC9
Gene Accession: BC000412
Reactivity: Human,Mouse
Host: Rabbit
Isotype: IgG
Immunogen: Recombinant protein of human CCDC106
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Conjugation: Unconjugated
Calculated MW:
Tissue Specificity/Positive Control:
Cellular Localization: Nucleus. Colocalizes with p53/TP53.
Storage: Store at -20C. Avoid freeze / thaw cycles.

Product Link: https://www.elabscience.com/p-ccdc106_polyclonal_antibody-31081.html
Manual Link: https://www.elabscience.com/viewpdf-31081-elabscience-E-AB-11038.PDF