Product Type: Antibody
Descritpion: The protein encoded by this gene is a bifunctional enzyme that catalyzes the oxidative conversion of delta(5)-ene-3-beta-hydroxy steroid, and the oxidative conversion of ketosteroids. It plays a crucial role in the biosynthesis of all classes of hormonal steroids. This gene is predominantly expressed in the adrenals and the gonads. Mutations in this gene are associated with 3-beta-hydroxysteroid dehydrogenase, type II, deficiency. Alternatively spliced transcript variants have been found for this gene.
Research Areas: Cancer, Metabolism, Signal transduction
Recommended Dilutions: IHC 1:25-1:100
Size: 200 uL
Gene Accession: BC038419
Immunogen: Recombinant protein of human HSD3B2
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Tissue Specificity/Positive Control: Expressed in adrenal gland, testis and ovary.
Cellular Localization: Endoplasmic reticulum,endoplasmic reticulum,endoplasmic reticulum membrane,smooth endoplasmic reticulum membrane,Mitochondrion,mitochondrial inner membrane,mitochondrial intermembrane space,mitochondrial membrane,Other locations:integral component of membrane
Storage: Store at -20C. Avoid freeze / thaw cycles.
Product Link: https://www.elabscience.com/p-hsd3b2_polyclonal_antibody-31352.html
Manual Link: https://www.elabscience.com/viewpdf-31352-elabscience-E-AB-11312.PDF