Product Type: Antibody
Descritpion: This gene encodes a major cytoplasmic protein which is the only known constituent common to submembranous plaques of both desmosomes and intermediate junctions. This protein forms distinct complexes with cadherins and desmosomal cadherins and is a member of the catenin family since it contains a distinct repeating amino acid motif called the armadillo repeat. Mutation in this gene has been associated with Naxos disease. Alternative splicing occurs in this gene; however, not all transcripts have been fully described.
Research Areas: Cancer, Signal transduction
Recommended Dilutions: WB 1:1000-1:5000, IHC 1:50-1:200
Size: 200 uL
Gene Accession: BC011865
Immunogen: Recombinant protein of human JUP
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Calculated MW: 82kDa
Tissue Specificity/Positive Control:
Cellular Localization: Cell junction>adherens junction. Cell junction>desmosome. Cytoplasm>cytoskeleton. Membrane. Cytoplasmic in a soluble and membrane-associated form.
Storage: Store at -20C. Avoid freeze / thaw cycles.
Product Link: https://www.elabscience.com/p-catenin_gamma_polyclonal_antibody-31384.html
Manual Link: https://www.elabscience.com/viewpdf-31384-elabscience-E-AB-11344.PDF