TAB3 Polyclonal Antibody

Supplier: Elabscience
Product Type: Antibody
Clonality: Polyclonal
Descritpion: The product of this gene functions in the NF-kappaB signal transduction pathway. The encoded protein, and the similar and functionally redundant protein MAP3K7IP2/TAB2, forms a ternary complex with the protein kinase MAP3K7/TAK1 and either TRAF2 or TRAF6 in response to stimulation with the pro-inflammatory cytokines TNF or IL-1. Subsequent MAP3K7/TAK1 kinase activity triggers a signaling cascade leading to activation of the NF-kappaB transcription factor. The human genome contains a related pseudogene. 
Research Areas: Cancer, Epigenetics and Nuclear Signaling, Immunology, Signal transduction
Applications: WB,IHC,ELISA
Recommended Dilutions: WB 1:1000-1:5000, IHC 1:50-1:200
Size: 200 uL
Concentration: 0.2mg/mL
Swissprot: Q8N5C8
Gene Accession: BC032526
Reactivity: Human,Mouse
Host: Rabbit
Isotype: IgG
Immunogen: Recombinant protein of human TAB3
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Conjugation: Unconjugated
Calculated MW: 79kDa
Tissue Specificity/Positive Control: Widely expressed. Constitutively overexpressed in certain tumor tissues. Isoform 1 is a major transcript while isoform 2 is a minor transcript.
Cellular Localization: Cytosol,Endosome membrane,Extracellular region or secreted,extracellular exosome,Plasma Membrane
Storage: Store at -20C. Avoid freeze / thaw cycles.

Product Link: https://www.elabscience.com/p-tab3_polyclonal_antibody-31420.html
Manual Link: https://www.elabscience.com/viewpdf-31420-elabscience-E-AB-11380.PDF