ZNRF1 Polyclonal AntibodyE-AB-11668
Product Type: Antibody
Descritpion: This gene encodes an E3 ubiquitin-protein ligase that plays a role in neural-cell differentiation. Overexpression of this gene causes neurite-like elongation. The encoded protein contains both a zinc finger and a RING finger motif and is localized in the endosome/lysosome compartment, indicating that it may be involved in ubiquitin-mediated protein modification, and in synaptic vessicle membranes in neurons.
Research Areas: Cell Biology
Recommended Dilutions: WB 1:200-1:1000, IHC 1:50-100
Size: 200 uL
Gene Accession: NP_115644
Immunogen: Synthetic peptide of human ZNRF1
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Calculated MW: 24kDa
Tissue Specificity/Positive Control: Expressed primarily in the nervous system, with expression higher in developing brain relative to adult. Expressed at low levels in testis and thymus.
Cellular Localization: Endosome. Lysosome. Membrane. Cytoplasmic vesicle>secretory vesicle>synaptic vesicle membrane. Associated with synaptic vesicle membranes in neurons.
Storage: Store at -20C. Avoid freeze / thaw cycles.
Product Link: https://www.elabscience.com/p-znrf1_polyclonal_antibody-39687.html
Manual Link: https://www.elabscience.com/viewpdf-39687-elabscience-E-AB-11668.PDF