Product Type: Antibody
Descritpion: This gene encodes a member of the POP family of proteins containing three putative transmembrane domains. This gene is expressed in cardiac and skeletal muscle and may play an important role in development of these tissues. The mouse ortholog may be involved in the regeneration of adult skeletal muscle and may act as a cell adhesion molecule in coronary vasculogenesis. Three transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Dec 2010]
Research Areas: Signal transduction
Recommended Dilutions: WB 1:500-1:2000, IHC 1:50-100
Size: 200 uL
Immunogen: Recombinant protein of human BVES
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Calculated MW: 41kDa
Tissue Specificity/Positive Control: Expressed in epithelial cells (at protein level). Expressed in fetal and adult heart and skeletal muscle.
Cellular Localization: Lateral cell membrane. Cell junction>tight junction. Membrane. Colocalizes with VAMP3 at the cell-cell contact in cardiac and skeletal muscle (By similarity). Its movement from the cytoplasm to membrane is an early event occurring concurrently with cell-cell contact. Colocalizes in epithelial cells with OCLN and TJP1 in an apical-lateral position within the z axis. Detected at cell-cell contact but never observed at the free surface of epithelial cells.
Storage: Store at -20C. Avoid freeze / thaw cycles.
Product Link: https://www.elabscience.com/p-bves_polyclonal_antibody-39704.html
Manual Link: https://www.elabscience.com/viewpdf-39704-elabscience-E-AB-11685.PDF