Product Type: Antibody
Descritpion: This gene encodes a member of the basic helix-loop-helix (BHLH) family of transcription factors. The protein activates transcription by binding to the E box (5'-CANNTG-3'). Dimerization with other BHLH proteins is required for efficient DNA binding. This protein plays a role in the neuronal commitment and differentiation and in the generation of olfactory and autonomic neurons. Mutations in this gene may contribute to the congenital central hypoventilation syndrome (CCHS) phenotype in rare cases.
Research Areas: Cancer, Epigenetics and Nuclear Signaling, Neuroscience
Recommended Dilutions: IHC 1:25-1:100
Size: 200 uL
Gene Accession: NP_004307
Immunogen: Synthetic peptide of human ASCL1
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Tissue Specificity/Positive Control:
Cellular Localization: Nucleus.
Storage: Store at -20C. Avoid freeze / thaw cycles.
Product Link: https://www.elabscience.com/p-ascl1_polyclonal_antibody-31736.html
Manual Link: https://www.elabscience.com/viewpdf-31736-elabscience-E-AB-12280.PDF